Cullen School of Engineering


Dept. of Electrical & Computer Engineering
N308 Engineering Building 1
Houston, Texas 77004-4005
Phone: 713-743-4400
Fax: 713-743-4444
Department: ece [at] egr [dot] uh [dot] edu
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Dr. Badri Roysam

Department Chair

N325 Engineering Building 1

Houston, Texas 77204-4005

Tel: 713-743-4400 | Fax: 713-743-4444

Email: broysam [at] central [dot] uh [dot] edu


  • B. Tech., Electronics Engineering, Indian Institute of Technology, Madras, India
  • M.S., Electrical Engineering, Washington University, St. Louis, Missouri
  • D.Sc., Electrical Engineering, Washington University, St. Louis, Missouri

Professional Experience


Assistant Professor, Department of Electrical, Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY.


Associate Professor with Tenure, Department of Electrical, Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY.


Adjunct Professor, Biomedical Engineering Department, Rensselaer Polytechnic Institute, Troy, NY


Director, Center for Sub-Surface Sensing and Imaging Systems, a NSF Engineering Research Center Rensselaer component


Professor, Department of Electrical, Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY.


Associate Editor, IEEE Transactions on Information Technology in Biomedicine


Associate Editor, IEEE Transactions on Biomedical Engineering


Co-Director, Rensselaer Center for Open Source Computing


Professor and Chair of Electrical and Computer Engineering, University of Houston


Courses Taught at UH

  • ECE 6111 Seminar in Imaging and Image Analysis

Courses Taught at Other Institutions

  • Biological Image Analysis
  • Subsurface Sensing and Imaging Systems
  • Computer Architecture, Networks, and Operating Systems
  • Computer Organization and Logic Design
  • Parallel ComputationD

Awards and Honors

  • DIADEM Challenge, HHMI/NIH, September 2010
  • Collins Lecture, Harvard Medical School, Harvard University, September 2009
  • Questar III Excellence in K-12 Service, Rensselaer Polytechnic Institute, 2007
  • Engineering Research Excellence Award, Rensselaer Polytechnic Institute, 2005
  • Best Paper Award, IEEE Conference on Computer Vision and Pattern Recognition, 1999


Research Interests

  • Biological image analysis High-performance computing Brain tissue mapping and Neuroprosthetic devices Computational Immunology Subsurface sensing and imaging systems

Funded Research

  • Principal Investigator: Defense Advanced Research Agency Grant N66001-11-1-4015, “Multispectral 3-D Histology and Predictive Statistical technologies for Identifying the Critical Combination of factors Impacting Long-term Performance of Implanted Neuroprosthetics”

  • Principal Investigator: NIH Biomedical Research Partnerships Grant R01 EB005157, titled “Multi-dimensional Image Analysis Tools for Brain Tissue

  • Co-investigator: NIH Grant RO1 CA135509, “Genotype and phenotype predictors in therapy response in renal cell carcinoma”

  • Co-investigator: NIH Grant RO1 CA135509, “Genotype and phenotype predictors in therapy response in renal cell carcinoma”

  • Co-investigator: NIH Grant R01 DK046943-14, "GnRH Receptor Signaling Specificity"


Selected Publications

Selected Publications

  • Al-Kofahi Y, Lassoued W, Grama K, Nath SK, Zhu J, Oueslati R, Feldman M, Lee WM, Roysam B. Cell-based quantification of molecular biomarkers in histopathology specimens. Histopathology. 2011 Jul;59(1):40-54.

  • Narayanaswamy A, Wang Y, Roysam B. 3-D image pre-processing algorithms for improved automated tracing of neuronal arbors. Neuroinformatics. 2011 Sep;9(2-3):219-31.

  • Luisi J, Narayanaswamy A, Galbreath Z, Roysam B. The FARSIGHT trace editor: an open source tool for 3-D inspection and efficient pattern analysis aided editing of automated neuronal reconstructions. Neuroinformatics. 2011 Sep;9(2-3):305-15.

  • Choi SG, Ruf-Zamojski F, Pincas H, Roysam B, Sealfon SC. Characterization of a MAPK scaffolding protein logic gate in gonadotropes. Mol Endocrinol. 2011 Jun;25(6):1027-39.

  • Wang Y, Narayanaswamy A, Tsai CL, Roysam B. A broadly applicable 3-D neuron tracing method based on open-curve snake. Neuroinformatics. 2011 Sep;9(2-3):193-217.

  • Tsai CL, Lister JP, Bjornsson CS, Smith K, Shain W, Barnes CA, Roysam B. Robust, globally consistent and fully automatic multi-image registration and montage synthesis for 3-D multi-channel images. J Microsc. 2011 Aug;243(2):154-71.

  • Mukherjee A, Jenkins B, Fang C, Radke RJ, Banker G, Roysam B. Automated kymograph analysis for profiling axonal transport of secretory granules. Med Image Anal. 2011 Jun;15(3):354-67.

  • Melichar HJ, Li O, Herzmark P, Padmanabhan RK, Oliaro J, Ludford-Menting MJ, Bousso P, Russell SM, Roysam B, Robey EA. Quantifying subcellular distribution of fluorescent fusion proteins in cells migrating within tissues. Immunol Cell Biol. 2011 May;89(4):549-57.

  • Isse K, Grama K, Abbott IM, Lesniak A, Lunz JG, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJ. Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis. Clin Liver Dis. 2010 Nov;14(4):669-85.

  • Padfield D, Rittscher J, Roysam B. Coupled minimum-cost flow cell tracking for high-throughput quantitative analysis. Med Image Anal. 2011 Aug;15(4):650-68.

  • Kokovay E, Goderie S, Wang Y, Lotz S, Lin G, Sun Y, Roysam B, Shen Q, Temple S. Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling. Cell Stem Cell. 2010 Aug 6;7(2):163-73.

  • Seggio AM, Narayanaswamy A, Roysam B, Thompson DM. Self-aligned Schwann cell monolayers demonstrate an inherent ability to direct neurite outgrowth. J Neural Eng. 2010 Aug;7(4):046001.

  • Narayanaswamy A, Dwarakapuram S, Bjornsson CS, Cutler BM, Shain W, Roysam B. Robust adaptive 3-D segmentation of vessel laminae from fluorescence confocal microscope images and parallel GPU implementation. IEEE Trans Med Imaging. 2010 Mar;29(3):583-97.

  • Cohen AR, Gomes FL, Roysam B, Cayouette M. Computational prediction of neural progenitor cell fates. Nat Methods. 2010 Mar;7(3):213-8.

  • Al-Kofahi Y, Lassoued W, Lee W, Roysam B. Improved automatic detection and segmentation of cell nuclei in histopathology images. IEEE Trans Biomed Eng. 2010 Apr;57(4):841-52.